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Wednesday 19 August 2020

The Ketogenic Diet: Evidence for Optimism ...

The Ketogenic Diet: Evidence for Optimism but High-Quality Research Needed

ABSTRACT

For >50 y, dietary guidelines in the United States have focused on reducing intakes of saturated and total fat. However, rates of obesity and diabetes rose markedly throughout this period, with potentially catastrophic implications for public health and the economy. Recently, ketogenic diets have received substantial attention from the general public and nutrition research community. These very-low-carbohydrate diets, with fat comprising >70% of calories, have been dismissed as fads. However, they have a long history in clinical medicine and human evolution. Ketogenic diets appear to be more effective than low-fat diets for treatment of obesity and diabetes. In addition to the reductions in blood glucose and insulin achievable through carbohydrate restriction, chronic ketosis might confer unique metabolic benefits of relevance to cancer, neurodegenerative conditions, and other diseases associated with insulin resistance. Based on available evidence, a well-formulated ketogenic diet does not appear to have major safety concerns for the general public and can be considered a first-line approach for obesity and diabetes. High-quality clinical trials of ketogenic diets will be needed to assess important questions about their long-term effects and full potential in clinical medicine.

A century ago, the ketogenic diet was a standard of care in diabetes, used to prolong the life of children with type 1 diabetes and to control the symptoms of type 2 diabetes in adults. Because all forms of diabetes share a basic pathophysiological problem, carbohydrate intolerance, restriction of carbohydrate on a ketogenic diet (typically ≤50 g/d with >70% fat) often produced rapid and remarkable clinical improvement. Discovery of insulin in the 1920s enabled people with diabetes to control hyperglycemia on high-carbohydrate diets. However, the human toll and economic burden from diabetes complications continue to mount, despite increasingly sophisticated insulin analogs and drugs for associated conditions such as dyslipidemia, hypertension, and coagulopathy. Contrary to expectation, adoption of a higher-carbohydrate (lower-fat) diet by the US public in the second half of the 20th century could have contributed to the increasing prevalence of obesity, a major risk factor for type 2 diabetes. Despite commonly voiced concerns about the safety of, and lack of supporting evidence for, this putative fad, the ketogenic diet has a long track record—not only in clinical medicine but also through human evolution—providing evidence for optimism in the search for more effective dietary prevention and treatment of chronic diseases.


Please use the link given below to read much more about:

Carbohydrate Restriction Is More Effective than Fat Restriction for Obesity Treatment

Low-Carbohydrate Diets Show Promise for Diabetes Treatment

Low-Carbohydrate Diets Might Lower CVD Risk despite High Saturated Fat Content

Chronic Ketosis Might Provide Unique Metabolic Benefits

Ketogenic Diets Have a Long Track Record of Safety

There Is No Human Requirement for Dietary Fibre or Carbohydrate

All the above with detailed report plus conclusions, acknowledgements, notes and all references can be seen here

h/t to Dr Steve Parker Diabetic Mediterranean Diet Blog see here


Related Posts:
We knew how to reverse type two diabetes in 1917 - see here
Introduction to low-carb for beginners - see  here
Why low carb - see here
How Low Carb Can Help, plus a favourite low carb recipe - see here
What is LCHF Anyway - see here

This blog brings a variety of articles and recipe ideas, and it is important to note, not all may be suitable for you. If you may have any food allergies, or underlying health issues these must always be taken into account. If you are a diabetic and not sure how certain foods may affect your blood sugars, test is best, i.e. use a reliable meter.

All the best Jan

17 comments:

Lowcarb team member said...

If you have problems with the links, this is an alternative one
https://pubmed.ncbi.nlm.nih.gov/31825066/

Tom said...

...the US is messed up in many ways!

JFM said...

Another wonderful and informative post...thank you Jan ☕

Jeanie said...

Very interesting! Thanks for sharing, Jan!

Valerie-Jael said...

....And in Germany the deaths from diabetes have risen by 45%! Valerie

R's Rue said...

Very interesting.

Elephant's Child said...

Optimism is ALWAYS welcome. Thank you.

Bleubeard and Elizabeth said...

Really interesting article. I read it all, even though I'm not diabetic.

I'm not obese, but if I am on lockdown much longer, I may get that way! I've already gained two pounds since March 15. And that's bad for someone who should weight a MAX of 105 lbs, not 107. For my height of 4'11", 130 would be obese.

Christine said...

Thanks for this information.

Maria Rodrigues said...

A very interesting post. Thanks for sharing.
I apologize for my absence but I have works in my house and there is very little time available. My posts are scheduled and are being published.
Hugs

The Joy of Home with Martha Ellen said...

The Keto diet has really worked for me! I was diagnosed with pre-diabetes almost two years ago. I started this diet then and have reversed my condition and have lost a lot of weight in the process. Doctors do not like this diet in the US. Too bad!! It works.

aussie aNNie said...

Brilliant post and info. xx

CJ Kennedy said...

Thanks for the links.

Snowbird said...

What an interesting postJan.xxx

Conniecrafter said...

I have tried almost every diet out there, I haven't found one that I totally have settled on, in the end I have not been able to maintain any of them for over a year, when a whole set of foods are totally illuminated over time I have not been able to totally give things up for good, guess it probably is I don't have self control in that area, I have lost and then gained most back from every diet I have been on including the keto :( But I have a couple friends that have been able to stick to it a lot better than myself.

Bob Bushell said...

Nice diet.

Teresa said...

Siempre muy interesantes tus entradas. Muchos besos.