"Obesity, we're told, represents the next great disease epidemic and GPs should get on and treat it. This is despite the fact that all 'treatments' for obesity have been shown to be almost useless, often resulting in greater weight gain in the long-term.
But it is not just Asian Indians who refute the hypothesised link between obesity and type 2 diabetes. There are many others. Perhaps the most spectacular can be found in a condition known as Berardinelli-Seip syndrome. People affected by this syndrome have very little adipose tissue. Theoretically, therefore, they should have no problems with insulin resistance or type 2 diabetes. Not so. Every individual with Berardinelli-Seip suffers from insulin-resistant diabetes mellitus2.
On the other hand, the most highly 'obese' population in the world – Sumo wrestlers – has no problems with type 2 diabetes or impaired glucose tolerance."
http://www.pulsetoday.co.uk/story.asp?storycode=4010272
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