In a two-year study of 8,502 people with type 2 diabetes aged 65 and older, 12.4% of those who started therapy with a sulfonylurea drug had a heart attack or other heart problem, compared with 10.4% of those who started with metformin.
Additionally, people taking sulfonylurea drugs experienced heart problems sooner after starting treatment than those taking metformin.
Graham
http://diabetes.webmd.com/news/20110628/metformin-safer-for-heart-than-older-diabetes-drugs
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