Yet a small case series, published books and various anecdotal reports suggest a ketogenic diet may be the most promising tool we have for treating Alzheimer’s disease. A new publication in the journal Alzheimer’s & Dementia adds to the growing body of evidence.
Alzheimer’s & Dementia: APOE ε4, the door to insulin-resistant dyslipidemia and brain fog? A case study
The authors of this case report hypothesize that those with ApoE4 variants (a genetic variant that is known to increase the risk for Alzheimer’s disease) have reduced ability to clear the beta-amyloid plaque from the brain, and they may have reduced ability to transport lipids among the neurons, thus increasing the formation of reactive oxygen species. This combination places them at increased risk for developing Alzheimer’s disease, especially if they have any element of insulin resistance or type 2 diabetes.
With the mounting evidence that Alzheimer’s disease may result from insulin resistance in the brain and inability to properly utilize glucose as fuel, suddenly it makes sense why a ketogenic diet may be the ideal treatment.
The recently published case report highlights the beneficial effects of a keto diet on one individual with type 2 diabetes, Alzheimer’s disease, and the Apo E4 variant. After only 10 weeks on a clinically prescribed ketogenic diet, the subject improved his cognitive assessment score from mild dementia to normal, his HbA1c normalized from 7.8% to 5.5%, and his other metabolic biomarkers likewise improved.
This does not prove that a ketogenic diet will be the magical cure for Alzheimer’s disease, but it certainly is more encouraging than all of the pharmaceutical drug failures. Instead of targeting the amyloid plaques, as many drugs do, we are better off focusing on the metabolic changes that occur in the brain, helping the brain decrease insulin resistance, or even providing the brain with ketones as an alternative fuel source. The mounting anecdotal evidence gives us hope that the cure for a seemingly complex and devastating condition may be as simple as what we choose to eat. Stay tuned to our blog, as we will continue to report on the science as we learn more about the intersection between Alzheimer’s disease and ketogenic diets."
Many thanks for reading - if you would like to read other articles related to Alzheimer’s disease - please click on the link here
All the best Jan
This is very interesting info! Hugs...RO
we need all the help we can get in this area!!!!! I have also heard that a no sugar diet is good, there was a documentary about it,,that darn sugar,,,,,its a killer!!!
Quite an interesting study. My internet friend CJ will be glad to read this, I'm sure.
Good to be informed on whatever might help with this.
Nice to hear a help with this
Very important info that could potentially help many people. Valerie
I don't know to believe or not! Dad died, 7 months ago in the alzheimer. He was sick for 10 years
This is so interesting...I want to come back and re-read when I can concentrate more.
Very interesting. I hope a cure for Alzheimer's is found someday. It is such a devastating disease.
Thanks for sharing this information, it’s very thorough and so well done! I learned something new.
Wishing you a Happy Sunday!
Encouraging news. Thanks for the info.
Muy interesante. Un beso.
very interesting since this runs in my family
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