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Tuesday 24 April 2012

Rising HbA1c levels ‘predict diabetes’

HbA1c levels rise rapidly in the year before a diagnosis of type 2 diabetes, say Japanese researchers.

Their study looked at 1,722 individuals aged 26–80 years without diabetes and measured fasting plasma glucose and HbA1c were measured annually for a mean of 9.5 years. A diagnosis of diabetes was given to 193 people, who had a mean HbA1c level of over 38mmol/mol (5.6%) each year before diagnosis. Average blood glucose and HbA1c values throughout the observational period were significantly higher in incident cases compared with non-cases, with differences of 1.02 mmol/L and 18 mmol/mol (0.471%) higher, respectively.

In the entire group, marked increases in HbA1c of 20 mmol/mol (0.3%) per year and fasting plasma glucose of 0.63 mmol/L/year predicted a diagnosis of diabetes.

Professor Hirohito Sone, diabetologist at the University of Tsukuba Institute of Clinical Medicine, Tsukuba, Japan, said their findings showed the value of screening regularly in those at risk of diabetes.

I suggested three years ago on a certain forum, that testing plasma glucose and plasma insulin levels for at risk people, i.e. over weight or people with generations of diabetics in their family. Result a major argument and I was accused of being a scare monger by an ex mod. What possible use would it be he asked. I thought knowing possibly years in advance of all the health problems that can go with type two diabetes would be very useful. Many would not take head of the warning, but many would dump the carbs and get on there bikes. They would have a very early warning and change their lifestyles.

The mod “a simple carb loving person with diabetes, struggling with managing the condition and living a normal life” Got fired, I got banned. Funny old life eh.


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